Laboratory Manager, Translational Medicine

About AskBio

Asklepios BioPharmaceutical, Inc. (AskBio), a wholly owned and independently operated subsidiary of Bayer AG acquired in 2020, is a fully integrated AAV gene therapy company dedicated to developing life-saving medicines that have the potential to cure genetic diseases. The company maintains a portfolio of clinical programs across a range of neuromuscular, central nervous system, cardiovascular and metabolic disease indications with a clinical-stage pipeline that includes therapeutics for Pompe disease, Parkinson’s disease, and congestive heart failure, as well as out-licensed clinical indications for hemophilia and Duchenne muscular dystrophy. AskBio’s gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, UK, the company has generated hundreds of proprietary third generation AAV capsids and promoters, several of which have entered clinical testing. Founded in 2001 and an early innovator in the gene therapy field, the company holds more than 850 patents in areas such as AAV production and chimeric and self-complementary capsids. Learn more at www.askbio.com.

Position Overview

The Laboratory Manager, Translational Medicine, reporting to the Sr. Director, Translational Medicine will be responsible for management of the day-to-day operational logistics of multiple laboratories within the Translational Medicine and Product Development departments. This position will also support laboratory quality and regulatory requirements for sample management and equipment.

Job Responsibilities 

  • Organize, implement, coordinate, enforce and/or monitor quality assurance programs.
  • Ensure quality control and compliance procedures are followed and QC reports are up to date.
  • Clinical sample management including receiving, sample tracking using GCP complaint software (LIMS).
  • Order, receive, ship and track laboratory equipment and supplies in coordination with lab managers for other labs.
  • Establish and maintain an inventory system for reagents, supplies and equipment.
  • Track and perform equipment calibrations and preventative maintenance.
  • Maintain equipment use binders and SOPs.
  • Manage departmental budget.
  • Coordinate waste management (red bag and waste streams).
  • Perform lab tasks as needed, including but not limited to, equipment monitoring and calibration, reagent and media prep, processing and cryopreservation of primary cells/cell lines.

Required Education & Experience 

  • Bachelor’s degree.
  • 5 years GxP experience and lab management in cell biology, immunology, molecular biology or related field.

Preferred Skills

  • Ability to handle multiple projects/teams simultaneously.
  • Ability to work independently in a fast-paced, highly interactive environment with minimal supervision.
  • Excellent verbal and written communication skills.
  • Ability to build open and collaborative relationships and work effectively as a member of a multi-disciplinary team.