Research Associate II, Immunoassay Development

About AskBio

Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.

At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.

We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, and Spain.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people’s lives.

Our principles:

  • Advance innovative science by pushing boundaries.
  • Bring transformative therapeutics to patients in need. 
  • Provide an environment for employees to reach their fullest potential. 

Our values:

  • Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
  • Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
  • Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
  • Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
  • Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

We have an opportunity for a Research Associate II, Immunoassay Development to join the AskBio team in our Research Triangle Park (Durham), NC location and be part of our continued success!

Position Overview 

The Research Associate II (Immunology): Immuno Assay Development Associate, reporting to the Senior Scientist, Immunoassay, will be one of the main laboratory members who will have the opportunity to contribute to the measurement of antibodies to the different serotypes of AAV’s by performing Total and Neutralizing antibody tests. This is a great opportunity for someone wishing to expand their Cell Biology and Immunology lab abilities by assisting in the assessment of clinical samples and driving exploratory data analysis of clinical studies to advance programs to clinical trial stages.


  • Develop, optimize, and execute bioanalytical assays to support preclinical and early development programs, with a focus on ligand binding immunoassays (ELISA, MSD, and/or Octet).
  • Develop, validate, and run fit-for-purpose cell-based virus neutralization assays, ELISA-based assays, or other applicable serological assays.
  • Support sample analysis for non-clinical and clinical studies by working in a GLP/GCP compliant laboratory setting and Technical knowledge in key areas of cell culture and cell-based immunoassays.
  • Maintaining clear and effective method development documentation per GLP procedures and processes is a must.
  • Author and review project-specific technical reports, standard operating procedures, work instructions, protocols, and transfer reports, as well as other material related to project goals.
  • General laboratory assistance, including ordering and receiving lab supplies, preparation of reagents, and maintaining laboratory equipment.

Required Education and Experience

  • BA or BS degree in Biological Sciences with 4 – 6 years of relevant experience, or MS with 3-5 years of relevant experience.

Preferred Experience and Skills

  • Experience working in a GxP environment with Immunoassay development and validation experience.
  • 3-5 years experience working in a pharmaceutical or biotechnology environment.
  • Preferred experience in cell-based viral neutralization assays and mammalian cell culture required.
  • Laboratory experience with aseptic technique and biosafety level two labs.
  • Strong attention to detail and ability to collaborate and work in a team environment.
  • Good Computer skills including word processing, Excel, PowerPoint, Graphpad, JMP, and relevant scientific software.
  • Must be self-motivated, organized, capable of working independently, as well as a team contributor.
  • Must possess strong oral and written communication skills. Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally.

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or emailing us at