The AskBio AAV technology platform

Since our founding over 20 years ago and with more than 40 years of pioneering AAV research, our vision has always extended beyond therapeutic development. Making genetic medicine highly accurate, safe, and effective is vital to improving patient lives, and the science for finding missing or mutated genes to correct genetic disorders has greatly evolved. 

Equally important is ensuring that no matter where they live, every patient in need has cost-efficient access to genetic medicine.  It is why we consider our AAV technology platform our greatest patient innovation. Its components are shaping how we scale gene therapy manufacturing and lower cost.

It is this uncompromised vision that propelled the emergence of a world-class gene therapy technology platform.

AAVPlatform proven end-to-end capability results in technology to increase scale and lower costs of goods as well as translate into clinic faster, safer and with greater predictability.
AAVPlatform proven end-to-end capability results in technology to increase scale and lower costs of goods as well as translate into clinic faster, safer and with greater predictability.

AAVPlatform proven end-to-end capability results in technology to increase scale and lower costs of goods as well as translate into clinic faster, safer and with greater predictability.

Three essential components of the AskBio AAV platform

Capsids

A vast range of chimeric constructs to match any tropism and maximize transduction

Promoters

An expression cassette with gene control, regulation and inducible technology

Production

Pro10™, a high-yield suspension cell line with synthetic materials output, lowers cost

Ask Jude

“Gene therapy is changing lives. Overcoming the challenges of production, accessibility, and cost must also be a priority.”

R. Jude Samulski, PhD
Chief Scientific Officer and Co-Founder

dna

Cracking the code: Fast and scalable production of safer DNA

AskBio and TAAV Biomanufacturing Solutions are revolutionizing DNA with a plasmid alternative that is safer for patients and lowers cost of AAV therapeutics.

The dawning of enzymatic DNA »

GMP manufacturing

Clinical and commercial GMP manufacturing

Our extensive manufacturing facilities in San Sebastian, Spain, allow for high-yield output of AAV vectors for any serotype and for the production of neDNA™, a benchtop alternative to plasmid DNA.

Advance AAV production »

genetic researcher

Are you on the verge of the next great discovery?

Collaboration with researchers in leading institutions, bioscience organizations and patient advocacy programs is hard coded into our DNA.

Accelerate genetic discovery »