Careers in Gene Therapy

Let’s make history together

AskBio is a world-leading gene therapy company with unrivaled technology and a promising therapeutic pipeline, making us an exciting place full of promise, discovery and advancement. We are a fast-growing, patient-focused team that embraces collaboration, creative thinking and groundbreaking science to change lives.

Our headquarters are in Research Triangle Park, North Carolina, with European offices and facilities in Edinburgh, Scotland, and San Sebastián, Spain.

A benefits package worthy of our mission

We come to work each­­ day for a purpose greater than the job itself. For that reason, we offer employee benefits that reflect the importance of our work and the quality and skill of our people.

  • Collaborative and inclusive culture
  • Health, dental and vision insurance
  • 401(k) plan with company match
  • Health and dependent care flexible spending account
  • Life insurance
  • Short- and long-term disability insurance
  • 4 weeks of paid time off
  • 10 paid company holidays
  • 5 days annual sick leave
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths
  • Collaborative and inclusive culture
  • Employer Pension Scheme
  • Life insurance
  • Critical Illness Cover
  • Private Healthcare
  • 30 days paid company holidays plus bank holidays
  • Bike to work scheme
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths

Our Values

When you live an AskLife™, you join a team that embraces meaningful values to ensure our success.

Ask Life

We bring decades of experience in discovery and gene therapy development – from the bench to the bedside – that we want to share with the world.

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Driven by excellence and achievement, we have an unrivaled end-to-end gene therapy platform with foundational discoveries essential to the industry.

Boundless icon

We are not afraid of the impossible and continuously innovate to make gene therapies accessible to all those in need.

Enthusiastic Icon

We love what we do and wake up every day motivated by a much larger purpose to change lives and erase genetic disease.

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We are humbled by the enormity of our mission and its meaning to families. We hold a relentless commitment to advance science and clinical outcomes.

Browse Open Positions

Please review the following open positions and apply now to upload your resume.

  • Scientist II-IV Upstream Process Development

    This role develops upstream (cell culture) processes for production of rAAV vector gene therapies. We’re seeking candidates with BS, MS or PhD degrees (chemical engineering, bioengineering, biology, biochemistry, virology or related field) with 7+, 4+ or 1+ years’ experience in biologics process development of large molecule or cellular therapies.

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  • Research Associate | BioAssay

    The Research Associate will contribute to the development of immunogenicity assays in support of our gene therapy programs. This is an excellent opportunity for candidates looking to build experience in basic cell and molecular biology lab skills for planning and execution of preclinical studies that advance to clinical trials.

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  • Research Associate II Downstream

    This role will support experiments designed to optimize rAAV downstream processing and purification for gene therapy applications. Great opportunity for a recent undergraduate with 1-3 years of experience in laboratory research, preferably in recombinant protein/biomolecule purification development, technology transfer and/or bioprocess manufacturing.

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  • Sr. Director, GMP Quality

    This role is responsible for establishing and maintaining AskBio’s GMP Quality Management System and ensuring corporate compliance with all applicable GMP regulations through the development and oversight of a robust quality management program. 

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  • Project Manager Associate CMC

    This role interfaces with project teams and external suppliers to plan and coordinate timely execution of CMC activities. The candidate will be responsible for project logistics and documentation and ensures key project management tools are used to drive project delivery and information dissemination to key stakeholders.

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  • Medical Director

    Role will develop clinical development strategies and study designs for pre-IND/IND submissions and support ongoing clinical trials in neuromuscular, CNS and metabolic disease indications.  S/he will integrate the knowledge base of scientific mechanisms and non-clinical studies into cogent endpoints and monitoring methods and play a significant role in devising amendments and monitoring strategies for ongoing studies.

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  • Research Associate II

    We’re seeking a Research Associate with an MS in molecular biology, biochemistry or other relevant discipline with 0-2 (BS with 0-5) years of progressive post-degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Scientist I-III Flow Cytometry Specialist

    We are seeking a Flow Cytometry Specialist to support our preclinical and clinical AAV gene therapy programs. The ideal candidate will have expertise in multiparameter flow cytometry from instrument set up and maintenance, to panel design, assay development and qualification. You’ll be the primary point of contact for flow cytometry related lab operations on the Translational Medicine team.

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  • Innate Scientist II-III

    We are seeking a highly motivated Innate Scientist. The successful candidate will support our discovery efforts, as well as preclinical and clinical AAV gene therapy programs, and independently design, prosecute and interpret experimental studies that characterize gene therapy candidates and contribute to lead selection/optimization. 

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  • Project Manager

    The successful candidate will have a comprehensive knowledge of drug development, advanced knowledge of scheduling and resource forecasting software (e.g., MS Project), as well as the definitions, standards and associated systems and tools, and may support several different types of schedules in the clinical development plan. Cardiovascular experience required.

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  • Sr Scientist | DNA Manufacturing/Process Development Group Lead

    This position provides planning and execution of DNA manufacturing and experiments designed to optimize DNA production, purification and scalability and will lead a group of scientists while being hands-on at the bench.

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  • Senior Director | Pharmacology/Toxicology

    We are looking for a Sr Director, Pharmacology/Toxicology to serve as a key scientist and manager for developing and executing preclinical and clinical strategies to support our pipeline of gene therapy products. This individual will coordinate and manage various studies leading to pre-IND packages, INDs, and eventually BLAs for an array of clinical development projects.

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  • FP&A Manager

    We are adding an FP&A Manager to our Finance team to lead budgeting, financial forecasting, reporting, financial modeling and processes, execute month-end and quarter-end variance analysis, conduct monthly variance reviews, and forecasting with department leaders. This role will also maintain rolling forecasts, long-range models and plans.   

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  • Research Associate, Non-Clinical Manufacturing

    We have an opening for a Manufacturing Research Associate to manufacture and assist in analytical characterization of research and GLP-grade recombinant adeno-associated virus (rAAV) vectors to support capsid technology development, our intellectual property portfolio, and progression of internal and external early-stage gene therapy programs.

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  • Vice President, Process and Analytical Development

    This senior-level role will provide technical, operational and strategic leadership and expertise in the development, tech transfer, manufacturing support and CMC operations of rAAV gene therapy products. S/he will serve as the head of the rAAV vector process and analytical development organization, which includes cell culture development, purification development, formulation development and analytical development.

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  • Scientist – Molecular/Cellular Biology, UK

    We have positions for a Scientist, Molecular/Cellular Biology to join the growing platform R&D team at our European headquarters in Edinburgh to develop the next generation of gene therapy treatments. Ideal candidates will have a background in molecular and cellular biology with knowledge of gene transcription and control mechanisms surrounding gene regulation.

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Equal Opportunity Employer

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email.