Careers in Gene Therapy

Let’s make history together

AskBio is a world-leading gene therapy company with unrivaled technology and a promising therapeutic pipeline, making us an exciting place full of promise, discovery and advancement. We are a fast-growing, patient-focused team that embraces collaboration, creative thinking and groundbreaking science to change lives.

Our headquarters are in Research Triangle Park, North Carolina, with European offices and facilities in Edinburgh, Scotland, and San Sebastián, Spain.

A benefits package worthy of our mission

We come to work each­­ day for a purpose greater than the job itself. For that reason, we offer employee benefits that reflect the importance of our work and the quality and skill of our people.

  • Collaborative and inclusive culture
  • Health, dental and vision insurance
  • 401(k) plan with company match
  • Health and dependent care flexible spending account
  • Life insurance
  • Short- and long-term disability insurance
  • 4 weeks of paid time off
  • 10 paid company holidays
  • 5 days annual sick leave
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths
  • Collaborative and inclusive culture
  • Employer Pension Scheme
  • Life insurance
  • Critical Illness Cover
  • Private Healthcare
  • 30 days paid company holidays plus bank holidays
  • Bike to work scheme
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths

Our Values

When you live an AskLife™, you join a team that embraces meaningful values to ensure our success.

Ask Life
Authoratative

Authoritative
We bring decades of experience in discovery and gene therapy development – from the bench to the bedside – that we want to share with the world.

Confident Icon

Confident
Driven by excellence and achievement, we have an unrivaled end-to-end gene therapy platform with foundational discoveries essential to the industry.

Boundless icon

Boundless
We are not afraid of the impossible and continuously innovate to make gene therapies accessible to all those in need.

Enthusiastic Icon

Enthusiastic
We love what we do and wake up every day motivated by a much larger purpose to change lives and erase genetic disease.

Responsible Icon

Responsible
We are humbled by the enormity of our mission and its meaning to families. We hold a relentless commitment to advance science and clinical outcomes.

Browse Open Positions

Please review the following open positions and apply now to upload your resume.

  • Medical Director

    Role will develop clinical development strategies and study designs for pre-IND/IND submissions and support ongoing clinical trials in neuromuscular, CNS and metabolic disease indications.  S/he will integrate the knowledge base of scientific mechanisms and non-clinical studies into cogent endpoints and monitoring methods and play a significant role in devising amendments and monitoring strategies for ongoing studies.

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  • Research Associate | Cell and Molecular Biology

    The Research Associate will will have an opportunity to learn and contribute to the development of immunogenicity assays in support of our gene therapy programs. This is an excellent opportunity for a candidate looking to build his/her experience in basic cell and molecular biology lab skills for planning and execution of preclinical studies that advance to clinical trials.

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  • Laboratory Manager

    This role will manage the day-to-day operational logistics of multiple laboratories within the Translational Medicine department. He/she will also support laboratory quality and regulatory requirements for sample management and equipment.

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  • Research Associate II in vivo Histology

    MS with 2 (BS with 3-5) years of progressive post-degree experience in gene therapy/vaccines/complex biologics (in the order of preference). Direct experience with characterization of rAAV gene therapy products is highly desired.

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  • Research Associate II Animal Technician

    This role will assist in animal husbandry and perform all study procedures, including animal handling, daily observations, sample collections (blood draws and processing), necropsies (and tissue processing, anesthesia, and other duties.

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  • Research Associate II

    We’re seeking a Research Associate with an MS in molecular biology, biochemistry or other relevant discipline with 0-2 (BS with 0-5) years of progressive post-degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Scientist I AAV Biology

    Seeking PhD in molecular biology, biochemistry or other relevant discipline with 0-3 (MS with 3-6, BS with 7-11) years of progressive post-degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Scientist II AAV Biology

    Seeking PhD in molecular biology, biochemistry or other relevant discipline with 2-6 (MS with 5-9, BS with 9-13) years of progressive post degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Sr. Scientist Group Leader in vivo Biology

    The Group Leader is expected to build and lead an in vivo biology (comparative medicine) team. IVB has responsibility for executing in vivo work related to rAAV vector evaluation and development and characterization of the animal disease models. IVB contributes to the delivery of the lead and back-up clinical candidate vectors for various indications.

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  • Scientist I-II Biomarker Specialist

    We’re seeking a scientist to support our biomarker discovery efforts for a pipeline of gene therapy candidates in development, preclinical and clinical stages. The successful candidate will be effective in the designing, execution and troubleshooting of lab experiments using in vitro, ex vivo and/or in vivo stimulation models and subsequent biomarker assay development.

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  • Scientist I-III Flow Cytometry Specialist

    We are seeking a Flow Cytometry Specialist to support our preclinical and clinical AAV gene therapy programs. The ideal candidate will have expertise in multiparameter flow cytometry from instrument set up and maintenance, to panel design, assay development and qualification. You’ll be the primary point of contact for flow cytometry related lab operations on the Translational Medicine team.

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  • Innate Scientist II-III

    We are seeking a highly motivated Innate Scientist. The successful candidate will support our discovery efforts, as well as preclinical and clinical AAV gene therapy programs, and independently design, prosecute and interpret experimental studies that characterize gene therapy candidates and contribute to lead selection/optimization. 

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  • Project Manager

    The successful candidate will have a comprehensive knowledge of drug development, advanced knowledge of scheduling and resource forecasting software (e.g., MS Project), as well as the definitions, standards and associated systems and tools, and may support several different types of schedules in the clinical development plan. Cardiovascular experience required.

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  • Sr Scientist – DNA Manufacturing/Process Development Group Lead

    This position provides planning and execution of DNA manufacturing and experiments designed to optimize DNA production, purification and scalability and will lead a group of scientists while being hands-on at the bench.

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  • Senior Director | Pharmacology/Toxicology

    We are looking for a Sr Director, Pharmacology/Toxicology to serve as a key scientist and manager for developing and executing preclinical and clinical strategies to support our pipeline of gene therapy products. This individual will coordinate and manage various studies leading to pre-IND packages, INDs, and eventually BLAs for an array of clinical development projects.

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  • Sr Research Associate | Analytical Development

    This role will assist in the design, development, qualification and execution of analytical assays to support in-process analytics, process development, non-clinical and GMP rAAV vector manufacturing. You’ll provide analytical test methods development, qualification and validation support for future non-GMP and GMP drug product release.

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  • Research Associate | Analytical Support

    This position will provide analytical assays to support our process development and non-GMP manufacturing teams. You’ll handle the execution and data analysis of molecular biology analytical test methods to support manufacturing process technology improvements and non-GMP rAAV vector release testing.

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  • Scientist – Upstream Process Development

    This role will develop upstream (cell culture) processes for production of recombinant adeno-associated viral (rAAV) vector gene therapies and work as part of a team on upstream process development, scale-up, optimization, characterization and transfer of projects.

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  • Senior Associate Scientist | Molecular Biology

    We are seeking a molecular biology engineer for a Senior Associate Scientist position. This role is for a hands-on, lab-based research scientist with technical expertise in protein engineering, molecular biology and molecular virology. The candidate will be responsible for optimizing the molecular design and the characterization of our proteins and rAAV capsids.

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  • Senior Associate Scientist | Phage

    We are looking for a Senior Associate Scientist specialized in phage display and molecular biology. The candidate will participate as a team player in the isolation and optimization of antibodies/peptides using phage display and have a strong foundation in molecular biology and vector cloning.

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  • FP&A Manager

    We are adding an FP&A Manager to our Finance team to lead budgeting, financial forecasting, reporting, financial modeling and processes, execute month-end and quarter-end variance analysis, conduct monthly variance reviews, and forecasting with department leaders. This role will also maintain rolling forecasts, long-range models and plans.   

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  • Scientist I

    We are seeking an outstanding molecular biology engineer for a Scientist I position. This role is for a hands-on, lab-based research scientist with technical expertise in the field of protein engineering, molecular biology and molecular virology. The candidate will be responsible for optimizing the molecular design and the characterization of our proteins and rAAV capsids.

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  • Research Associate, Non-Clinical Manufacturing

    We have an opening for a Manufacturing Research Associate to manufacture and assist in analytical characterization of research and GLP-grade recombinant adeno-associated virus (rAAV) vectors to support capsid technology development, our intellectual property portfolio, and progression of internal and external early-stage gene therapy programs.

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  • Vice President, Process and Analytical Development

    This senior-level role will provide technical, operational and strategic leadership and expertise in the development, tech transfer, manufacturing support and CMC operations of rAAV gene therapy products. S/he will serve as the head of the rAAV vector process and analytical development organization, which includes cell culture development, purification development, formulation development and analytical development.

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  • Scientist – Molecular/Cellular Biology, UK

    We have positions for a Scientist, Molecular/Cellular Biology to join the growing platform R&D team at our European headquarters in Edinburgh to develop the next generation of gene therapy treatments. Ideal candidates will have a background in molecular and cellular biology with knowledge of gene transcription and control mechanisms surrounding gene regulation.

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  • Scientist – Analytical Development

    We are seeking a Scientist, Analytical Development, to assist in the design, development, qualification and execution of analytical assays to support in-process analytics, process development, non-clinical recombinant adeno-associated virus (rAAV) vector manufacturing and GMP rAAV vector manufacturing. This individual provides analytical test methods development, qualification and validation support for future non-GMP and GMP drug product release. 

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Equal Opportunity Employer

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email.