Careers in Gene Therapy

Let’s make history together

AskBio is a world-leading gene therapy company with unrivaled technology and a promising therapeutic pipeline, making us an exciting place full of promise, discovery and advancement. We are a fast-growing, patient-focused team that embraces collaboration, creative thinking and groundbreaking science to change lives.

Our headquarters are in Research Triangle Park, North Carolina, with European offices and facilities in Edinburgh, Scotland, and San Sebastián, Spain.

A benefits package worthy of our mission

We come to work each­­ day for a purpose greater than the job itself. For that reason, we offer employee benefits that reflect the importance of our work and the quality and skill of our people.

  • Collaborative and inclusive culture
  • Health, dental and vision insurance
  • 401(k) plan with company match
  • Health and dependent care flexible spending account
  • Life insurance
  • Short- and long-term disability insurance
  • 4 weeks of paid time off
  • 10 paid company holidays
  • 5 days annual sick leave
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths
  • Collaborative and inclusive culture
  • Employer Pension Scheme
  • Life insurance
  • Critical Illness Cover
  • Private Healthcare
  • 30 days paid company holidays plus bank holidays
  • Bike to work scheme
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths

Our Values

When you live an AskLife™, you join a team that embraces meaningful values to ensure our success.

Ask Life

We bring decades of experience in discovery and gene therapy development – from the bench to the bedside – that we want to share with the world.

Confident Icon

Driven by excellence and achievement, we have an unrivaled end-to-end gene therapy platform with foundational discoveries essential to the industry.

Boundless icon

We are not afraid of the impossible and continuously innovate to make gene therapies accessible to all those in need.

Enthusiastic Icon

We love what we do and wake up every day motivated by a much larger purpose to change lives and erase genetic disease.

Responsible Icon

We are humbled by the enormity of our mission and its meaning to families. We hold a relentless commitment to advance science and clinical outcomes.

Browse Open Positions

Please review the following open positions and apply now to upload your resume.

  • Principal Scientist – Pathology

    Lead a group of 1-3 histologists to ensure appropriate cell staining and tissue sectioning. DVM or equivalent required with Board certification in Veterinary Anatomic Pathology.

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  • Sr Principal Scientist

    The Principal Scientist will provide scientific guidance and leadership in the preclinical safety de-risking of AAV-based gene therapies.

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  • Sr Toxicologist/Pharmacologist

    This role will be a key member on multidisciplinary project teams to represent the toxicology function to define and implement nonclinical safety evaluation strategy and plan of novel candidate molecules.

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  • Histologist

    Independently perform advanced histology (slide QC, special stains, thin/thick sections, IHC, and serial/step sectioning). Seeking PhD in biological sciences or MS with 3+ years’ or BS with 5+ years’ relevant research experience.

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  • In Vivo Pharmacologist

    The In Vivo Pharmacologist will design/develop in vivo models of metabolic/CNS/liver diseases to characterize the efficiency of gene therapy constructs.

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  • Medical Safety Director

    This role is responsible for the leadership and oversight of investigational product safety in preclinical and clinical development and will interact with and influence other development and medical functions or leaders to ensure the successful development, design and implementation of comprehensive safety assessment protocols and plans.

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  • Scientist | Muscle Bioassay

    Seeking a Muscle Bioassay Scientist as subject matter expert in muscle and/or metabolism (preclinical, clinical, animal models, genetic diseases, etc.).

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  • Scientist | Liver Bioassay

    This role will provide subject matter expertise in liver diseases and liver-targeted therapies (preclinical, clinical, animal models, genetic diseases, acquired liver disease, chronic liver disease, liver inflammation, liver toxicity, etc.).

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  • Research Associate (in vivo)

    Seeking a candidate with an undergrad degree in Animal Science or related field with at 3-5+ years hands-on experience to provide in vivo dosing of vectors, capsids and therapeutic cassettes.

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  • Office Manager

    The office manager will lead the setup of our office in Columbus, OH and fully support the clinical and scientific staff to optimize office efficiency, while promoting a great employee and visitor experience.

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  • Clinical Trial Manager/Associate Director

    This role is responsible for day-to-day management of clinical study projects in our Columbus, OH location. Seeking candidate with a minimum of 3 years’ experience in clinical trial management, and experience with neurological or gene therapy studies is preferred.

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  • IT Support Engineer (UK)

    Reporting to the Director of Business Operations, Europe, with a dotted line to the VP of IT, you will work as part of a virtual global IT team to support both system users and development projects across the UK, Europe and US.

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  • Lead Application & Support Engineer (Apple Mac)

    Duties include managing Mac support and configuration of all systems including clinical systems, vendor and account management, hardware setup and installation, hardware and software inventories, and maintenance of operating systems and training.

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  • Senior/Principal Scientist (UK)

    Join our rapidly expanding platform R&D team in Edinburgh UK to develop the next generation of gene therapy treatments. This senior scientific post has project management accountabilities and potentially line management responsibilities.

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  • R&D Scientist – Molecular/Cellular Biology (UK)

    The ideal candidates will have a good grounding in molecular and cellular biology with knowledge of gene transcription and control mechanisms surrounding gene regulation.

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  • R&D Animal Technician/Scientist (UK)

    This role could suit an HND/degree-qualified candidate with several years of animal lab experience behind them. We are seeking individuals with relevant experience from a similar scientific environment.

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  • Cell Line Development Scientist/Senior Scientist (UK)

    Join our rapidly expanding R&D team in Edinburgh to develop next-generation cell lines used to produce AAVs for gene therapies. The ideal candidate will have a solid grounding in virology and cell line development.

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  • Research Associate, Analytical Support

    This position supports the R&D AAV vector manufacturing team. Must have 1-3 years’ work experience and skills in qPCR, ddPCR, PCR, sequencing, ELISA and other molecular biology and biochemistry assay techniques.

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  • Manufacturing Scientist

    This role is responsible for rAAV vector manufacturing for research- and GLP-grade studies to support rAAV technology improvements and progression of early stage gene therapy programs. Seeking 1-3 (or 2-5) years’ experience in bioprocess manufacturing and technology transfer, preferably in rAAV and/or recombinant protein/biomolecule bioprocess manufacturing.

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  • Research Associate, Non-Clinical Manufacturing

    This role will manufacture and assist in analytical characterization of research- and GLP-grade recombinant adeno-associated virus (rAAV) vectors to support capsid technology development, our IP portfolio, and progression of early stage gene therapy programs.

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  • Scientist II AAV Biology

    Seeking PhD in molecular biology, biochemistry or other relevant discipline with 2-6 (MS with 5-9, BS with 9-13) years of progressive post degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Senior Scientist – Downstream Process Development

    This role provides development and execution of experiments designed to optimize rAAV downstream processing and purification for gene therapy applications. Requires MS or PhD in an engineering discipline (chemical/biochemical engineering, or equivalent).

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  • Research Associate I-III, Molecular Biology

    We have an opportunity for a Research Associate I-III with hands-on experience in molecular biology techniques (e.g. RNA/DNA isolation, molecular cloning, plasmid purification, Western blotting, qPCR, RT-qPCR, ELISA).

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  • Scientist II-IV Upstream Process Development

    This role develops upstream (cell culture) processes for production of rAAV vector gene therapies. We’re seeking candidates with BS, MS or PhD degrees (chemical engineering, bioengineering, biology, biochemistry, virology or related field) with 7+, 4+ or 1+ years’ experience in biologics process development of large molecule or cellular therapies.

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  • Project Manager Associate CMC

    This role interfaces with project teams and external suppliers to plan and coordinate timely execution of CMC activities. The candidate will be responsible for project logistics and documentation and ensures key project management tools are used to drive project delivery and information dissemination to key stakeholders.

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  • Research Associate II

    We’re seeking a Research Associate with an MS in molecular biology, biochemistry or other relevant discipline with 0-2 (BS with 0-5) years of progressive post-degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Innate Scientist II-III

    We are seeking a highly motivated Innate Scientist. The successful candidate will support our discovery efforts, as well as preclinical and clinical AAV gene therapy programs, and independently design, prosecute and interpret experimental studies that characterize gene therapy candidates and contribute to lead selection/optimization. 

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  • Sr Scientist | DNA Manufacturing/Process Development Group Lead

    This position provides planning and execution of DNA manufacturing and experiments designed to optimize DNA production, purification and scalability and will lead a group of scientists while being hands-on at the bench.

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  • Vice President, Process and Analytical Development

    This senior-level role will provide technical, operational and strategic leadership and expertise in the development, tech transfer, manufacturing support and CMC operations of rAAV gene therapy products. S/he will serve as the head of the rAAV vector process and analytical development organization, which includes cell culture development, purification development, formulation development and analytical development.

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Equal Opportunity Employer

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email.