Careers in Gene Therapy

Let’s make history together

AskBio is a world-leading gene therapy company with unrivaled technology and a promising therapeutic pipeline, making us an exciting place full of promise, discovery and advancement. We are a fast-growing, patient-focused team that embraces collaboration, creative thinking and groundbreaking science to change lives.

Our headquarters are in Research Triangle Park, North Carolina, with European offices and facilities in Edinburgh, Scotland, and San Sebastián, Spain.

A benefits package worthy of our mission

We come to work each­­ day for a purpose greater than the job itself. For that reason, we offer employee benefits that reflect the importance of our work and the quality and skill of our people.

  • Collaborative and inclusive culture
  • Health, dental and vision insurance
  • 401(k) plan with company match
  • Health and dependent care flexible spending account
  • Life insurance
  • Short- and long-term disability insurance
  • 4 weeks of paid time off
  • 13 paid company holidays
  • 5 days annual sick leave
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths
  • Collaborative and inclusive culture
  • Employer Pension Scheme
  • Life insurance
  • Critical Illness Cover
  • Private Healthcare
  • 30 days paid company holidays plus bank holidays
  • Bike to work scheme
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths

Our Values

When you live an AskLife™, you join a team that embraces meaningful values to ensure our success.

Ask Life
Authoratative

Authoritative
We bring decades of experience in discovery and gene therapy development – from the bench to the bedside – that we want to share with the world.

Confident Icon

Confident
Driven by excellence and achievement, we have an unrivaled end-to-end gene therapy platform with foundational discoveries essential to the industry.

Boundless icon

Boundless
We are not afraid of the impossible and continuously innovate to make gene therapies accessible to all those in need.

Enthusiastic Icon

Enthusiastic
We love what we do and wake up every day motivated by a much larger purpose to change lives and erase genetic disease.

Responsible Icon

Responsible
We are humbled by the enormity of our mission and its meaning to families. We hold a relentless commitment to advance science and clinical outcomes.

Browse Open Positions

Please review the following open positions and apply now to upload your resume.

  • Head of Biostatistics

    This role is responsible for providing strategic and operational leadership to AskBio’s biostatistics and broad data sciences functions.

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  • Clinical Development Medical Director

    This role is responsible for one or more clinical programs across indications, involving one or multiple molecular entities.

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  • Senior Medical Safety Director, Medical Safety Director, or Associate Medical Safety Director

    This role is responsible for the leadership and oversight of investigational product safety in preclinical and clinical development.

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  • Analyst, Business Systems Administration

    This role is responsible for managing AskBio’s business applications, including Finance, Contract Management and Purchasing systems.

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  • Gene Editing Senior Scientist / Scientist III

    This role supports our discovery efforts as well as preclinical and clinical AAV gene therapy programs.

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  • Non-Clinical Manufacturing/Process Development Lab Manager

    This role is responsible for laboratory operations and supports quality and regulatory requirements for sample management and equipment.

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  • Research Associate III/Scientist I – Analytical Development

    This role will support the development and execution of cell-based assays for evaluation of vector candidates in support of our gene therapy programs. Seeking extensive tissue culture experience with multiple cell lines and prior experience in assay qualification/validation.

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  • Associate Director – Clinical Trial Manager

    This role will provide oversight of AskBio’s pipeline studies, including study conduct and CRO oversight and will be a key point of contact for study project management, communications, and daily operations for clinical INDs.

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  • Associate Director Medical Writing

    The Associate Director, Medical Writing will be responsible for providing clinical direction to team members, developing and writing content for their specific projects as well as reviewing scientific content created outside AskBio. This position will have direct interaction with leading key opinion leaders.

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  • Clinical Trial Associate/Senior Clinical Trial Associate

    This role supports the creation and maintenance of clinical trial records, including the Trial Master File (TMF), to maintain inspection readiness during our clinical trials. The CTA is an integral part of the study/trial team in assuring that all clinical trial paperwork is handled appropriately and that assigned TMFs are complete, accurate, and timely.

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  • Associate Director/Director Data Management

    The Associate Director/Director of Data Management provides oversight of all data management activities to research sites ensuring the quality and integrity of all databases used in AskBio sponsored trials.

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  • Business Development Manager (Viralgen Vector Core)

    The Business Development Manager is responsible for driving sales growth and overall commercial success of Viralgen Vector Core by setting and executing the go-to-market strategy and managing the commercial process of selling AAV manufacturing services to AAV developers. 

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  • Project Manager

    Create and maintain clinical program plans and track progress against key milestones and goals. The ideal candidate will have some R&D experience. Experience working with planning tools (e.g. MS Project) and strong organizational skills are required.

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  • Contract Specialist

    The Contract Specialist will work with our attorneys in creating and managing contracts and other documents. Candidate should have 2+ years in-house law/contracting department or law firm experience, as well as experience in the healthcare/life sciences industry.

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  • Sr. Clinical Research Associate

    We’re looking for a senior CRA to join AskBio in our Columbus, Ohio location as part of our core study team and work with the clinical trial managers to oversee site management and monitoring activities.

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  • Research Associate II (in vivo)

    This position will conduct experimental bench work and provide technical expertise in the development of rAAV gene therapy clinical candidate vectors. MS with 2 (BS with 3-5) years of progressive post-degree experience.

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  • Director/Sr Director, Analytical and Bioassays

    Seeking an experienced, highly motivated candidate to lead the development, qualification and GxP validation of in vitro bioassays to support our preclinical/clinical gene therapy programs. This role will lead bioassay development strategies and provide technical guidance to scientists.

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  • Sr Principal Scientist

    The Principal Scientist will provide scientific guidance and leadership in the preclinical safety de-risking of AAV-based gene therapies.

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  • Sr Toxicologist/Pharmacologist

    This role will be a key member on multidisciplinary project teams to represent the toxicology function to define and implement nonclinical safety evaluation strategy and plan of novel candidate molecules.

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  • Histologist

    Independently perform advanced histology (slide QC, special stains, thin/thick sections, IHC, and serial/step sectioning). Seeking PhD in biological sciences or MS with 3+ years’ or BS with 5+ years’ relevant research experience.

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  • In Vivo Pharmacologist

    The In Vivo Pharmacologist will design/develop in vivo models of metabolic/CNS/liver diseases to characterize the efficiency of gene therapy constructs.

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  • Medical Safety Director

    This role is responsible for the leadership and oversight of investigational product safety in preclinical and clinical development and will interact with and influence other development and medical functions or leaders to ensure the successful development, design and implementation of comprehensive safety assessment protocols and plans.

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  • Scientist | Muscle Bioassay

    Seeking a Muscle Bioassay Scientist as subject matter expert in muscle and/or metabolism (preclinical, clinical, animal models, genetic diseases, etc.).

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  • Scientist | Liver Bioassay

    This role will provide subject matter expertise in liver diseases and liver-targeted therapies (preclinical, clinical, animal models, genetic diseases, acquired liver disease, chronic liver disease, liver inflammation, liver toxicity, etc.).

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  • Research Associate (in vivo)

    Seeking a candidate with an undergrad degree in Animal Science or related field with at 3-5+ years hands-on experience to provide in vivo dosing of vectors, capsids and therapeutic cassettes.

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  • Clinical Trial Manager/Associate Director

    This role is responsible for day-to-day management of clinical study projects in our Columbus, OH location. Seeking candidate with a minimum of 3 years’ experience in clinical trial management, and experience with neurological or gene therapy studies is preferred.

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  • Senior/Principal Scientist (UK)

    Join our rapidly expanding platform R&D team in Edinburgh UK to develop the next generation of gene therapy treatments. This senior scientific post has project management accountabilities and potentially line management responsibilities.

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  • R&D Scientist – Molecular/Cellular Biology (UK)

    The ideal candidates will have a good grounding in molecular and cellular biology with knowledge of gene transcription and control mechanisms surrounding gene regulation.

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  • R&D Animal Technician/Scientist (UK)

    This role could suit an HND/degree-qualified candidate with several years of animal lab experience behind them. We are seeking individuals with relevant experience from a similar scientific environment.

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  • Cell Line Development Scientist/Senior Scientist (UK)

    Join our rapidly expanding R&D team in Edinburgh to develop next-generation cell lines used to produce AAVs for gene therapies. The ideal candidate will have a solid grounding in virology and cell line development.

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Equal Opportunity Employer

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email.