Careers in Gene Therapy

Let’s make history together

AskBio is a world-leading gene therapy company with unrivaled technology and a promising therapeutic pipeline, making us an exciting place full of promise, discovery and advancement. We are a fast-growing, patient-focused team that embraces collaboration, creative thinking and groundbreaking science to change lives.

Our headquarters are in Research Triangle Park, North Carolina, with European offices and facilities in Edinburgh, Scotland, and San Sebastián, Spain.

A benefits package worthy of our mission

We come to work each­­ day for a purpose greater than the job itself. For that reason, we offer employee benefits that reflect the importance of our work and the quality and skill of our people.

  • Collaborative and inclusive culture
  • Health, dental and vision insurance
  • 401(k) plan with company match
  • Health and dependent care flexible spending account
  • Life insurance
  • Short- and long-term disability insurance
  • 4 weeks of paid time off
  • 13 paid company holidays
  • 5 days annual sick leave
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths
  • Collaborative and inclusive culture
  • Employer Pension Scheme
  • Life insurance
  • Critical Illness Cover
  • Private Healthcare
  • 30 days paid company holidays plus bank holidays
  • Bike to work scheme
  • Business casual
  • Career advancement
  • On-site gym and beautiful walking paths

Our Values

When you live an AskLife™, you join a team that embraces meaningful values to ensure our success.

Ask Life

We bring decades of experience in discovery and gene therapy development – from the bench to the bedside – that we want to share with the world.

Confident Icon

Driven by excellence and achievement, we have an unrivaled end-to-end gene therapy platform with foundational discoveries essential to the industry.

Boundless icon

We are not afraid of the impossible and continuously innovate to make gene therapies accessible to all those in need.

Enthusiastic Icon

We love what we do and wake up every day motivated by a much larger purpose to change lives and erase genetic disease.

Responsible Icon

We are humbled by the enormity of our mission and its meaning to families. We hold a relentless commitment to advance science and clinical outcomes.

Browse Open Positions

Please review the following open positions and apply now to upload your resume.

  • Scientist II

    We have an opportunity for a Scientist II to join the AskBio team in our Research Triangle Park, NC location.

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  • Research Associate II/III, Immunology

    The Research Associate II/III, Immunology at AskBio will be one of the key laboratory members who will have an opportunity to learn and contribute to the development of immunology cell or ligand-based assays in support of our gene therapy programs.

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  • Project Manager, Operations

    We are seeking a highly motivated scientist to join our growing Program Management team. The selected individual will play an important role in supporting AskBio’s programs.

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  • Scientist I/II, Gene Editing

    We are seeking a highly motivated scientist to join our growing R&D team. The successful candidate will support our preclinical in vivo gene editing programs in Research and Development.

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  • Clinical Development Medical Director

    This role is responsible for one or more clinical programs across indications, involving one or multiple molecular entities.

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  • Non-Clinical Manufacturing/Process Development Lab Manager

    This role is responsible for laboratory operations and supports quality and regulatory requirements for sample management and equipment.

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  • Research Associate III/Scientist I – Analytical Development

    This role will support the development and execution of cell-based assays for evaluation of vector candidates in support of our gene therapy programs. Seeking extensive tissue culture experience with multiple cell lines and prior experience in assay qualification/validation.

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  • Associate Director – Clinical Trial Manager

    This role will provide oversight of AskBio’s pipeline studies, including study conduct and CRO oversight and will be a key point of contact for study project management, communications, and daily operations for clinical INDs.

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  • Associate Director Medical Writing

    The Associate Director, Medical Writing will be responsible for providing clinical direction to team members, developing and writing content for their specific projects as well as reviewing scientific content created outside AskBio. This position will have direct interaction with leading key opinion leaders.

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  • Clinical Trial Associate/Senior Clinical Trial Associate

    This role supports the creation and maintenance of clinical trial records, including the Trial Master File (TMF), to maintain inspection readiness during our clinical trials. The CTA is an integral part of the study/trial team in assuring that all clinical trial paperwork is handled appropriately and that assigned TMFs are complete, accurate, and timely.

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  • Associate Director/Director Data Management

    The Associate Director/Director of Data Management provides oversight of all data management activities to research sites ensuring the quality and integrity of all databases used in AskBio sponsored trials.

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  • Sr. Clinical Research Associate

    We’re looking for a senior CRA to join AskBio in our Columbus, Ohio location as part of our core study team and work with the clinical trial managers to oversee site management and monitoring activities.

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  • Research Associate II (in vivo)

    This position will conduct experimental bench work and provide technical expertise in the development of rAAV gene therapy clinical candidate vectors. MS with 2 (BS with 3-5) years of progressive post-degree experience.

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  • Sr Principal Scientist

    The Principal Scientist will provide scientific guidance and leadership in the preclinical safety de-risking of AAV-based gene therapies.

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  • Scientist II/III, Bioassay Muscle

    We are seeking an experienced and highly motivated metabolic scientist to develop organ specific bioassays, lead pre-qualification, and GXP pre-validation of in vitro/in vivo muscle bioassays to support preclinical and clinical gene therapy programs.

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  • Scientist II/III, Bioassay Liver

    We are seeking an experienced and highly motivated hepatic scientist to develop organ specific bioassays, lead pre-qualification, and GXP pre-validation of in vitro/in vivo liver bioassays to support preclinical and clinical gene therapy programs.

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  • Research Associate (in vivo)

    Seeking a candidate with an undergrad degree in Animal Science or related field with at 3-5+ years hands-on experience to provide in vivo dosing of vectors, capsids and therapeutic cassettes.

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  • Senior/Principal Scientist (UK)

    Join our rapidly expanding platform R&D team in Edinburgh UK to develop the next generation of gene therapy treatments. This senior scientific post has project management accountabilities and potentially line management responsibilities.

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  • R&D Scientist – Molecular/Cellular Biology (UK)

    The ideal candidates will have a good grounding in molecular and cellular biology with knowledge of gene transcription and control mechanisms surrounding gene regulation.

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  • R&D Animal Technician/Scientist (UK)

    This role could suit an HND/degree-qualified candidate with several years of animal lab experience behind them. We are seeking individuals with relevant experience from a similar scientific environment.

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  • Cell Line Development Scientist/Senior Scientist (UK)

    Join our rapidly expanding R&D team in Edinburgh to develop next-generation cell lines used to produce AAVs for gene therapies. The ideal candidate will have a solid grounding in virology and cell line development.

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  • Manufacturing Scientist

    This role is responsible for rAAV vector manufacturing for research- and GLP-grade studies to support rAAV technology improvements and progression of early stage gene therapy programs. Seeking 1-3 (or 2-5) years’ experience in bioprocess manufacturing and technology transfer, preferably in rAAV and/or recombinant protein/biomolecule bioprocess manufacturing.

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  • Research Associate, Non-Clinical Manufacturing

    This role will manufacture and assist in analytical characterization of research- and GLP-grade recombinant adeno-associated virus (rAAV) vectors to support capsid technology development, our IP portfolio, and progression of early stage gene therapy programs.

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  • Senior Scientist – Downstream Process Development

    This role provides development and execution of experiments designed to optimize rAAV downstream processing and purification for gene therapy applications. Requires MS or PhD in an engineering discipline (chemical/biochemical engineering, or equivalent).

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  • Research Associate I-III, Molecular Biology

    We have an opportunity for a Research Associate I-III with hands-on experience in molecular biology techniques (e.g. RNA/DNA isolation, molecular cloning, plasmid purification, Western blotting, qPCR, RT-qPCR, ELISA).

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  • Scientist II-IV Upstream Process Development

    This role develops upstream (cell culture) processes for production of rAAV vector gene therapies. We’re seeking candidates with BS, MS or PhD degrees (chemical engineering, bioengineering, biology, biochemistry, virology or related field) with 7+, 4+ or 1+ years’ experience in biologics process development of large molecule or cellular therapies.

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  • Research Associate II

    We’re seeking a Research Associate with an MS in molecular biology, biochemistry or other relevant discipline with 0-2 (BS with 0-5) years of progressive post-degree experience in gene therapy/vaccines/complex biologics product development roles (in the order of preference). Direct experience with development of rAAV gene therapy products.

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  • Sr Scientist | DNA Manufacturing/Process Development Group Lead

    This position provides planning and execution of DNA manufacturing and experiments designed to optimize DNA production, purification and scalability and will lead a group of scientists while being hands-on at the bench.

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Equal Opportunity Employer

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements.

If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email.